"Stuff" in one's nostrils is mucus, flaking skin, etc. I examine each nostril once a day, making it a part of my routine like brushing teeth, flossing after meals, showe... more"Stuff" in one's nostrils is mucus, flaking skin, etc. I examine each nostril once a day, making it a part of my routine like brushing teeth, flossing after meals, showering, etc.